A Likelihood-Based Trait-Model-Free Approach for Linkage Detection of Binary Trait
نویسندگان
چکیده
منابع مشابه
A likelihood-based trait-model-free approach for linkage detection of binary trait.
Trait-model-free (or "allele-sharing") approach to linkage analysis is a popular tool in genetic mapping of complex traits, because of the absence of explicit assumptions about the underlying mode of inheritance of the trait. The likelihood framework introduced by Kong and Cox (1997, American Journal of Human Genetics 61, 1179-1188) allows calculation of accurate p-values and LOD scores to test...
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ژورنال
عنوان ژورنال: Biometrics
سال: 2009
ISSN: 0006-341X
DOI: 10.1111/j.1541-0420.2009.01270.x